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  • Singh, H., Sahgal, P., Kapner, K., Corsello, S., Gupta, H., Gujrathi, R., Li, Y., Cherniack, A., El Alam , R., Kerfoot, J., Andrews, E., Lee, A., Nambiar, C., Hannigan, A., Remland, J., Brais, L., Leahy, M., Rubinson, D., Schlechter, B., Meyerson, M., Kuang, Y., Paweletz, C., Lee, J., Quintanilha, J., Aguirre, A., Perez, K., Huffman, B., Rossi, H., Abrams, T., Kabraji, S., Trusolino, L., Bertotti, A., Sicinska, E., Parikh, A., Wolpin, B., Schrock, A., Giannakis, M., Ng, K., Meyerhardt, J., Hornick, J., Sethi, N., & Cleary, J. (2024). RAS/RAF co-mutation and ERBB2 copy number modulates HER2 heterogeneity and responsiveness to HER2-directed therapy in colorectal cancer. Clinical Cancer Research. https://doi.org/10.1158/1078-0432.CCR-23-2581
  • Ji, W., Byun, W. S., Lu, W., Zhu, X., Donovan, K., Dwyer, B., Che, J., Yuan, L., Abulaiti, X., Corsello, S., Fischer, E., Zhang, T., & Gray, N. (2023). Proteomics-Based Discovery of First-in-Class Chemical Probes for Programmed Cell Death Protein 2 (PDCD2). Angewandte Chemie, e202308292. https://doi.org/10.1002/anie.202308292
  • Lu, W., Fan, M., Ji, W., Tse, J., Yu, I., Ficarro, S., Tavares, I., Che, J., Kim, A., Zhu, X., Boghossian, A., Rees, M., Ronin, M., Roth, J., Hinshaw, S., Nabet, B., Corsello, S., Kwiatkowski, N., Marto, J., Zhang, T., & Gray, N. (2023). Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors. Journal of Medicinal Chemistry, 66, 4617–4632. https://doi.org/10.1021/acs.jmedchem.2c01548
  • Keller, R., Mazor, T., Sholl, L., Aguirre, A., Singh, H., Sethi, N., Bass, A., Nagaraja, A., Brais, L., Hill, E., Hennessey, C., Cusick, . M., Fitz, C. ., Zwiesler, Z., Siegel, E., Ovalle, A., Trukhanov, P., Hansel, J., Shapiro, G., Abrams, T., Biller, L., Chan, J., Cleary, J., Corsello, S., Enzinger, A., Enzinger, P., Mayer, R., McCleary, N., Meyerhardt, J., Ng, K., Patel, A., Perez, K., Rahma, O., Rubinson, D., Wisch, J., Yurgelun, M., Hassett, M., MacConaill, L., Schrag, D., Cerami, E., Wolpin, . B., Nowak, J., & Giannakis, M. . (2023). Programmatic Precision Oncology Decision Support for Patients With Gastrointestinal Cancer. JCO Precision Oncology, 7, e2200342. https://doi.org/10.1200/PO.22.00342
  • Rohban, M., Fuller, A., Tan, C., Goldstein, J., Syangtan, D., Gutnick, A., DeVine, A., Nijsure, M., Rigby, M., Sacher, J., Corsello, S., Peppler, G., Bogaczynska, M., Boghossian, A., Ciotti, G., Hands, A., Mekareeya, . A., Doan, M., Gale, J., Derynck, R., Turbyville, T., Boerckel, J., Singh, S., Kiessling, L., Schwarz, T., Varelas, X., Wagner, F., Kafri, R., Eisinger-Mathason, T. K., & Carpenter, A. (2022). Virtual screening for small-molecule pathway regulators by image-profile matching. Cell Systems, 13(9), 724-736.e9. https://doi.org/10.1016/j.cels.2022.08.003
  • Fang, L., Ford-Roshon, D., Russo, M., O’Brien, C., Xiong, X., Gurjao, C., Grandclaudon, M., Raghavan, S., Corsello, S., Carr, S., Udeshi, N., Berstler, J., Sicinska, E., Ng, K., & Giannakis, M. (2022). RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition. Nature Communications, 13(1), 3181. https://doi.org/10.1038/s41467-022-30794-7
  • Tsvetkov, P., Coy, S., Petrova, B., Dreishpoon, M., Verma, A., Abdusamad, M., Rossen, J., Joesch-Cohen, L., Humeidi, R., Spangler, R., Eaton, J., Frenkel, E., Kocak, M., Corsello, S., Lutsenko, S., Kanarek, N., Santagata, S., & Golub, T. (2022). Copper induces cell death by targeting lipoylated TCA cycle proteins. Science, 375(6586), 1254-1261. https://doi.org/10.1126/science.abf0529
  • Słabicki, M., Kozicka, Z., Petzold, G., Li, Y.-D., Manojkumar, M., Bunker, R., Donovan, K., Sievers, Q., Koeppel, J., Suchyta, D., Sperling, A., Fink, E., Gasser, J., Wang, L., Corsello, S., Sellar, R., Jan, M., Gillingham, D., Scholl, C., Fröhling, S., Golub, T., Fischer, E., Thomä, N., & Ebert, B. (2020). The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K. Nature, 585(7824), 293-297. https://doi.org/10.1038/s41586-020-2374-x
  • Corsello, S., Nagari, R., Spangler, R., Rossen, J., Kocak, M., Bryan, J., Humeidi, R., Peck, D., Wu, X., Tang, A., Wang, V., Bender, S., Lemire, E., Narayan, R., Montgomery, P., Ben-David, U., Garvie, C., Chen, Y., Rees, M., Lyons, N., McFarland, J., Wong, B., Wang, L., Dumont, N., O’Hearn, P., Stefan, E., Doench, J., Harrington, C., Greulich, H., Meyerson, M., Vazquez, F., Subramanian, A., Roth, J., Bittker, J., Boehm, J., Mader, C., Tsherniak, A., & Golub, T. (2020). Discovering the anticancer potential of non-oncology drugs by systematic viability profiling. Nature Cancer, 1, 235-248. https://doi.org/10.1038/s43018-019-0018-6
  • Gurjao, C., Liu, D., Hofree, M., AlDubayan, S., Wakiro, I., Su, M.-J., Felt, K., Gjini, E., Brais, L., Rotem, A., Rosenthal, M., Rozenblatt-Rosen, O., Rodig, S., NG, K., Van Allen, E., Corsello, S., Ogino, S., Regev, A., Nowak, J., & Giannakis, M. (2019). Intrinsic Resistance to Immune Checkpoint Blockade in a Mismatch Repair-Deficient Colorectal Cancer. Cancer Immunology Research, 7(8), 1230-1236. https://doi.org/10.1158/2326-6066.CIR-18-0683
  • Subramanian, A., Narayan, R., Corsello, S., Peck, D., Natoli, T., Lu, X., Gould, J., Davis, J., Tubelli, A., Asiedu, J., Lahr, D., Hirschman, J., Liu, Z., Donahue, M., Julian, B., Khan, M., Wadden, D., Smith, I., Lam, D., Liberzon, A., Toder, C., Bagul, M., Orzechowski, M., Enache, O., Piccioni, F., Johnson, S., Lyons, N., Berger, A., Shamji, A., Brooks, A., Vrcic, A., Flynn, C., Rosains, J., Takeda, D., Hu, R., Davison, D., Lamb, J., Ardlie, K., Hogstrom, L., Greenside, P., Gray, N., Clemons, P., Silver, S., Wu, X., Zhao, W.-N., Read-Button, W., Wu, X., Haggarty, S., Ronco, L., Boehm, J., Schreiber, S., Doench, J., Bittker, J., Root, D., Wong, B., & Golub, T. (2017). A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles. Cell, 171(6), 1437-1452.e17. https://doi.org/10.1016/j.cell.2017.10.049
  • Ghazani, A., Oliver, N., St. Pierre, J., Garofalo, A., Rainville, I., Hiller, E., Treacy, D., Rojas-Rudilla, V., Wood, S., Bair, E., Parello, M., Huang, F., Giannakis, M., Wilson, F., Stover, E., Corsello, S., Nguyen, T., Rana, H., Church, A., Lowenstein, C., Cibulskis, C., Amin-Mansour, A., Heng, J., Brais, L., Santos, A., Bauer, P., Waldron, A., Lo, P., Gorman, M., Lydon, C., Welch, M., McNamara, P., Gabriel, S., Sholl, L., Lindeman, N., Garber, J., Joffe, S., Van Allen, E., Gray, S., Jänne, P., Garraway, L., & Wagle, N. (2017). Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study. Genetics In Medicine, 19(7), 787-795. https://doi.org/10.1038/gim.2016.191
  • Corsello, S., Bittker, J., Liu, Z., Gould, J., McCarren, P., Hirschman, J., Johnston, S., Vrcic, A., Wong, B., Khan, M., Asiedu, J., Narayan, R., Mader, C., Subramanian, A., & Golub, T. (2017). The Drug Repurposing Hub: a next-generation drug library and information resource. Nature Medicine, 23(4), 405-408. https://doi.org/10.1038/nm.4306
  • Kim, E., Ilic, N., Shrestha, Y., Zou, L., Kamburov, A., Zhu, C., Yang, X., Lubonja, R., Tran, N., Nguyen, C., Lawrence, M., Piccioni, F., Bagul, M., Doench, J., Chouinard, C., Wu, X., Hogstrom, L., Natoli, T., Tamayo, P., Horn, H., Corsello, S., Lage, K., Root, D., Subramanian, A., Golub, T., Getz, G., Boehm, J., & Hahn, W. (2016). Systematic Functional Interrogation of Rare Cancer Variants Identifies Oncogenic Alleles. Cancer Discovery, 6(7), 714-726. https://doi.org/10.1158/2159-8290.CD-16-0160
  • Wilson, F., Johannessen, C., Piccioni, F., Tamayo, P., Kim, J., Van Allen, E., Corsello, S., Capelletti, M., Calles, A., Butaney, M., Sharifnia, T., Gabriel, S., Mesirov, J., Hahn, W., Engelman, J., Meyerson, M., Root, D., Jänne, P., & Garraway, L. (2015). A functional landscape of resistance to ALK inhibition in lung cancer. Cancer Cell, 27(3), 397-408. https://doi.org/10.1016/j.ccell.2015.02.005
  • Corsello, S., Roti, G., Ross, K., Chow, K., Galinsky, I., DeAngelo, D., Stone, R., Kung, A., Golub, T., & Stegmaier, K. (2009). Identification of AML1-ETO modulators by chemical genomics. Blood, 113(24), 6193-6205. https://doi.org/10.1182/blood-2008-07-166090
  • Corsello, S., & Kantoff, P. (2008). Does androgen deprivation therapy in men with prostate cancer increase cardiovascular morbidity?. Nature Clinical Practice Urology, 5(2), 80-81. https://doi.org/10.1038/ncpuro1015
  • Stegmaier, K., Corsello, S., Ross, K., Wong, J., Deangelo, D., & Golub, T. (2005). Gefitinib induces myeloid differentiation of acute myeloid leukemia. Blood, 106(8), 2841-2848. https://doi.org/10.1182/blood-2005-02-0488